The trotting miss, driven by, stopped the clock in a stakes record time of 1:53.3 at odds of 28-1.
MacDonell left alertly in the early stages as he settled Samira Hanover in third, behind the two favourites Rose Run Oriana () and Rockin With Dewey ( ) at the opening quarter in a quick :26.4.
As the field of 10 headed towards the half, Standing My Ground () made a brush to the lead at the half in :56.2.
That left Frisky Magic first over around the final turn, which allowed Samira Hanover to angle to the outside to catch cover.
Heavily-favoured Rose Run Oriana popped out of the two-hole before three-quarters in 1:25 and quickly took over command.
Down the stretch, Rose Run Oriana was in an all-out drive from Waples, but MacDonell showed his charge open road and Samira Hanover wore down the tempo-setter in deep stretch to win by half a length. Rockin With Dewey split horses late in the mile to finish third.
Trained byfor P C Wellwood Enterprises Inc, Steve Organ, William Weaver and A K Malik Stable, Samira Hanover increased her career bankroll to $104,280.
The four-year-old daughter ofcelebrated her sixth career victory.
She paid $59.40 to win.
The Lifetime Dream Series is for four and five-year-old trotting mares, who are non-winners of $200,000 lifetime as of December 31, 2013.
Also on Monday's programme, the opening round of the Tie Silk Series kicked off with a pair of $15,000 divisions.
Driverguided both Musical Spell and Entranced to victory in their respective connections.
Sent off as the co-favourite at odds of 2-1, Musical Spellwent gate-to-wire in 1:57.2 to capture the first division.
The son oflaid down panels of :27.2, :58.4 and 1:29.1, before fending off a late challenge from the other co-favourite Windsun Revenge ( ) to stop the clock in 1:57.2. Gangio ( ) finished third.
Trained by Mike Guitard for owner Haryott Stables Inc, Musical Spell remains a perfect two-for-two to start his 2014 campaign. The bay gelding increased his bankroll to $15,500.
He paid $6.80 to win.
One race later, Saftic used the same tactics as Entranced stopped the clock in a speedy 1:54.4, a North American season's record.
The Garth Gorden trainee cruised through panels of :27.1, :56 and 1:25.1, before scoring a comfortable one and a half length win. So Not Cool () came on for second, over even-money favourite Verdi ( ).
Gorden also co-owns the son ofwith Gary Green and Bernard Tobin. After banking $21,000 as a rookie last season, Entranced celebrated his second career victory and new lifetime best.
He paid $11.90 to win.
The Tie Silk Series is for three-year-olds trotters, who are non-winners of $30,000 in 2013.
More stakes action continues on Thursday night as two $15,000 divisions of the Tie Silk kicks off in the opening round. Post time is set for 7:25 p.m.
by Greg Gangle, for WEG